3D Bioprinting: Manufacturing the Human Heart

Every day, the organ shortage crisis takes away lives of 17 patients (Health Resources & Services Administration, 2022). The number who require transplants significantly exceeds possible donors, and consequently, most pass while waiting for a matching donor organ. To address this issue, 3D bioprinting was suggested as method by which could receive functioning replica their own biocompatible This manuscript will cover in depth materials—the bioink—and printing methods that are widely used various researchers field. More specifically, analyze compare natural bioinks—alginate collagen—and synthetic bioinks—Gelatin methacryloyl polycaprolactone. It then introduce two major methods—extrusion-based inkjet-based printing—and advantages disadvantages each method. Finally, highlight successful applications cardiology using aforementioned bioinks methods.